Design:: This was a retrospective clinical study carried out at tertiary care center, done over a period of 3 years (Aug 2018 to Aug 2021) , with average follow up of 1-3 years.

Setting: In both procedures, patients were positioned in lithotomy position, with McIndoe's vaginoplasty under spinal anaesthesia and Davydov's under general anaesthesia

Patients or Participants: 27 patients with MRKH syndrome were taken, 11 underwent McIndoe’s vaginoplasty and 16 had laparoscopic Davydov’s vaginoplasty

Interventions: Mcindoe's vaginoplasty was done by creating a space between bladder and rectum and mold covered with amnion put. In davydov's procedure, patient's own peritoneum was used for lining neovagina

Measurements and Main Results: Operating time, post-op vaginal length and coital dysfunction postoperatively were compared

All had primary amenorrhea with absent vagina. Mean age at presentation was similar in both groups (16.6 years) while age at surgery (21.7 years vs 23.9 vs years) was higher in Davydov’s as compared to McIndoe’s group, the difference was not statistically significant (p=0.27). Duration of surgery was more in laparoscopic Davydov’s as compared to McIndoe’s vaginoplasty group (101.33 +/- 19.80 min vs and 33.88 +/- 7.20 p <0.001). Neovaginal length was similar in both group (6.7 cm vs 6.5 cm), p =0.6. Of 27 patients, 26 (96.2%) used mould at night for 6 weeks. One woman developed vaginal stenosis following McIndoes vaginoplasty. Before surgery,3 patients were married and during an average follow up of 1-3 years,13 more got married. Of 16 married women (59.25%), all reported satisfactory sexual intercourse.

Conclusion: Both the procedure are safe and effective surgical methods for neovaginal creation. Davydov’s peritoneal vaginoplasty has the advantage that native tissue is used to cover the vagina, but it requires surgical expertise and more operating time as compared to McIndoe’s technique.